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5-FU Clinical Trials

15 actively recruiting trials across 4 locations

▼ -1 trial since May 2026

Also known as: 5 Fluorouracil, Adrucil, Fluorouracil, fluorouracil

Pipeline

Phase 1: 3Phase 2: 6Phase 3: 2Phase 1/2: 3

Top Sponsors

  • Fudan University2
  • Zhejiang Doer Biologics Co., Ltd.1
  • West China Hospital1
  • UNC Lineberger Comprehensive Cancer Center1
  • Qilu Hospital of Shandong University1

Indications

  • Cancer15
  • Colorectal Cancer2
  • Metastatic Colorectal Cancer2
  • Gastroesophageal Carcinoma1
  • Diffuse Pleural Mesothelioma1

Other11 trials

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors
Phase 1/2
ARTEMIS-102: HS-20093 Combinations in Patients with Advanced Metastatic Colorectal Cancer
Phase 1
Evaluation of the Preliminary Efficacy and Safety of DR30206 in Combination With Standard Therapy in Patients With Gastrointestinal Cancer
Phase 1/2
First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2)
Phase 2
Hypofractionated Radiotherapy Combined With NALIRIF, PD-1 Antibody in Locally Recurrent Rectal Cancer(NOVELTY-R)
Phase 2
Liposomal Irinotecan + Oxaliplatin + Bevacizumab Versus Liposomal Irinotecan + 5-FU/LV
Phase 1/2
Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer
Phase 2
Phase II Study of Irinotecan Liposomes in First-line Treatment of Metastatic Colorectal Cancer
Phase 2
Preoperative Chemoradiotherapy Combined With Consolidation or Induction NALIRIFOX in Rectal Cancer.
N/A
Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB
Phase 3
Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma
Phase 3

Los Angeles, California1 trial

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

Research Site

Phase 2

Boston, Massachusetts1 trial

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Massachusetts General Hospital

Phase 1

Basking Ridge, New Jersey1 trial

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Phase 1

Chapel Hill, North Carolina1 trial

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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