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Balstilimab Clinical Trials

17 actively recruiting trials across 10 locations

No change since May 2026

Also known as: AGEN 2034, AGEN-2034, AGEN2034, AGEN2034, anti-PD-1 antibody, BAL +3 more

Pipeline

Early 1: 1Phase 1: 3Phase 2: 8Phase 3: 2Phase 1/2: 2Phase 2/3: 1

Top Sponsors

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins2
  • Memorial Sloan Kettering Cancer Center2
  • Weill Medical College of Cornell University1
  • University of Southern California1
  • The Netherlands Cancer Institute1

Indications

Other5 trials

Assessment of the Safety and Efficacy of Balstilimab for the Treatment of Relapsed/Refractory Lymphomas (IMMONC0001)
Phase 2
Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma
Phase 3
Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas
Phase 3
Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations
Phase 2/3
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)
Phase 2

Baltimore, Maryland2 trials

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Phase 1/2
KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Sidney Kimmel Comprehensive Cancer Center

Phase 1

Basking Ridge, New Jersey2 trials

A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

Phase 2
A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

Phase 2

Duarte, California1 trial

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

City of Hope Medical Center

Phase 2

Fullerton, California1 trial

Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients With KRAS-Mutant Metastatic Colorectal Cancer

Saint Jude Medical Center / Providence Medical Foundation

Phase 1

Orange, California1 trial

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Children's Health Orange County (CHOC)

Phase 1

Miami, Florida1 trial

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

University of Miami

Phase 2

Chicago, Illinois1 trial

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Northwestern University

Phase 2

Boston, Massachusetts1 trial

Botensilimab, Balstilimab, and SBRT in Colorectal Cancer

Massachusetts General Hospital

Early 1

New York, New York1 trial

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Weill Cornell Medicine/NewYork-Presbyterian Hospital

Phase 2

Houston, Texas1 trial

A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab

MD Anderson Cancer Center

Phase 1/2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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