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Becotatug Vedotin Clinical Trials

8 actively recruiting trials

▲ +2 trials since August 2026

Also known as: MRG003

Pipeline

Phase 1: 1Phase 2: 5Phase 3: 2

Top Sponsors

  • West China Hospital1
  • Tianjin Medical University Second Hospital1
  • Sun Yat-sen University1
  • Ming-Yuan Chen1
  • Jiyan Liu1

Indications

  • Cancer8
  • Nasopharyngeal Carcinoma (NPC)2
  • Other EGFR-positive Pediatric Solid Tumors Deemed Eligible by the Investigator1
  • Diffuse Intrinsic Pontine Gliomas1
  • Atypical Teratoid/Rhabdoid Tumors1

Other8 trials

A Phase II Clinical Trial of Anti-EGFR Antibody-drug Conjugate (ADC) Combined With or Without Immune Checkpoint Inhibitors in the Neoadjuvant Treatment of Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma
Phase 2
A Study of Becotatug Vedotin (MRG003) Combined With Epirubicin as Neoadjuvant Therapy for EGFR-Positive, Unresectable Recurrent Sinonasal Adenoid Cystic Carcinoma
Phase 2
Becotatug Vedotin Combined With a PD-1 Inhibitor in the Treatment of Locally Advanced Recurrent Nasopharyngeal Carcinoma.
Phase 2
Becotatug Vedotin Plus Sintilimab in Locoregionally Advanced NPC
Phase 3
EGFR-ADC (Becotatug Vedotin) Combined With PD-1 Inhibitor (Pucotenlimab) in Neoadjuvant Treatment of Advanced Penile Cancer
Phase 2
Efficacy and Safety of SBRT Combined With Becotatug Vedotin (MRG003) in EGFR-Positive Metastatic Tumor Patients With Oligometastases
Phase 3
Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors
Phase 1
Phase II Study of Becotatug Vedotin Plus Pucotenlimab for Advanced Refractory Solid Tumors With EGFR-Positive
Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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