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BMS-986504 Clinical Trials

8 actively recruiting trials across 4 locations

No change since May 2026

Also known as: MRTX1719, Navlimetostat

Pipeline

Early 1: 1Phase 1: 3Phase 2: 2Phase 2/3: 2

Top Sponsors

  • Bristol-Myers Squibb5
  • Nader Sanai1
  • Memorial Sloan Kettering Cancer Center1
  • M.D. Anderson Cancer Center1

Indications

  • Cancer8
  • Lung Cancer2
  • Gastroesophageal Carcinoma1
  • Diffuse Pleural Mesothelioma1
  • MTAP-deleted Pancreatic Cancer1

Other2 trials

A Study to Assess Safety, Tolerability and Drug Levels of BMS-986504 in Participants With Advanced Solid Tumors
Phase 1
A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion
Phase 1

Anchorage, Alaska2 trials

A Study of Navlimetostat (BMS-986504) in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion (MountainTAP-9)

Alaska Oncology and Hematology

Phase 2
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Alaska Oncology and Hematology

Phase 2/3

Phoenix, Arizona2 trials

A Study Comparing BMS-986504 in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

Mayo Clinic in Arizona - Phoenix

Phase 2/3
Clinical Trial of BMS-986504 in Recurrent GBM Patients

St. Joseph's Hospital and Medical Center

Early 1

Basking Ridge, New Jersey1 trial

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Phase 1

Houston, Texas1 trial

A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer

MD Anderson Cancer Center

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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