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Esketamine Clinical Trials

10 actively recruiting trials across 3 locations

▼ -1 trial since June 2026

Also known as: (S)-Ketamine, E, Group of patients undergoing gastroenteroscopies with esketamine, JNJ-54135419

Pipeline

Early 1: 1Phase 3: 1Phase 4: 3

Top Sponsors

University of Zagreb1
Tianjin Medical University General Hospital1
Second Affiliated Hospital, School of Medicine, Zhejiang University1
Second Affiliated Hospital of Wenzhou Medical University1
Nanfang Hospital, Southern Medical University1

Indications

Depression6
Major Depressive Disorder3
Esketamine3
Anxiety3
Preoperative Sedation of Children1

Other7 trials

Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia

Phase 4

Effect of Esketamine on Postoperative Depression、Gut Microbiota、Bispectral Index Data of Depression Patients Undergoing Breast Cancer Operation (ESPOD-BI)

Phase 4

Effect of Low-dose EsketaMine on dElirium in High-risk Elderly Patients uNdergoing elecTive Surgery (ELEMENT)

N/A

Esketamine Combined With Remimazolam on Postoperative Sleep Disturbance and Anxiety in Patients

N/A

Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease

N/A

Metabolic Profiling of Esketamine Treatment in Depressive Disorder

Personalized DBS Targeting for Treating Depression

Early 1

Birmingham, Alabama1 trial

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

University of Alabama at Birmingham

Phase 3

Iowa City, Iowa1 trial

University of Iowa Interventional Psychiatry Service Patient Registry

University of Iowa Health Care

Boston, Massachusetts1 trial

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Massachusetts General Hospital

Phase 4

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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