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Hyperpolarized 13C-Pyruvate Clinical Trials

10 actively recruiting trials across 3 locations

No change since May 2026

Also known as: (13C) pyruvate, HP 13C, HP [1-13C]pyruvate, HP-13C, Hyperpolarized (HP) carbon^13 (13C)-pyruvate +2 more

Pipeline

Early 1: 1Phase 1: 2Phase 2: 3Phase 1/2: 2

Top Sponsors

University of Maryland, Baltimore3
University of California, San Francisco2
University of Texas Southwestern Medical Center1
Sunnybrook Health Sciences Centre1
Robert Bok, MD, PhD1

Indications

Cancer10
Prostate Cancer2
Warburg Effect1
Heart Disease1
Cardiometabolic Syndrome1

San Francisco, California4 trials

Hyperpolarized 13C MRI as a Biomarker in Advanced Solid Tumors

University of California, San Francisco

Phase 1/2

Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer

University of California, San Francisco

Lenvatinib Plus Pembrolizumab in Well Differentiated G3 Neuroendocrine Tumors

University of California, San Francisco

Phase 2

Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer

University of California, San Francisco

Early 1

Baltimore, Maryland3 trials

HP Pyruvate MRI in Cancers

University of Maryland Medical Center

Phase 1/2

Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

Rosy Njonkou Tchoquessi

Phase 1

Utility of Hyperpolarized 13C-pyruvate Metabolic Magnetic Resonance Imaging

University of Maryland Medical Center

Phase 2

Other2 trials

Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body

Phase 2

Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)

Phase 1

Dallas, Texas1 trial

Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI)

UT Southwestern Medical Center

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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