liposomal irinotecan Clinical Trials

9 actively recruiting trials across 4 locations

▼ -1 trial since June 2026

Also known as: (Onivyde®), Nal-IRI, New Neoadjuvant Treatment Approach, irinotecan liposome, nal-IRI

Pipeline

Phase 1: 1Phase 2: 5Phase 3: 1Phase 1/2: 1

Top Sponsors

Hebei Medical University Fourth Hospital2
University of Wisconsin, Madison1
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology1
St. Jude Children's Research Hospital1
Peking University People's Hospital1

Indications

Cancer9
Rectal Cancer2
Osteosarcoma Metastatic1
Rectal Cancer, Adenocarcinoma1
Metastatic Pancreatic Adenocarcinoma1

Other5 trials

Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma

Phase 1/2

Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer

Phase 2

Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer

Phase 2

SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC

N/A

Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement

Phase 2

Fort Smith, Arkansas1 trial

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Mercy Cancer Center

Phase 3

Duarte, California1 trial

A Study of ASP3082 in Adults With Advanced Solid Tumors

City of Hope National Medical Center

Phase 1

Palo Alto, California1 trial

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

Stanford University

Phase 2

Madison, Wisconsin1 trial

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

University of Wisconsin Carbone Cancer Center

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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