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Lomustine Clinical Trials

8 actively recruiting trials across 5 locations

▼ -1 trial since May 2026

Also known as: 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU), 1-Nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-, Belustin, Belustine +16 more

Pipeline

Phase 1: 1Phase 2: 1Phase 3: 4Phase 2/3: 1

Top Sponsors

  • Vastra Gotaland Region1
  • University of California, Davis1
  • The University of Texas Health Science Center at San Antonio1
  • Jasper Gerritsen1
  • Global Coalition for Adaptive Research1

Indications

  • Cancer8
  • Glioblastoma5
  • Glioblastoma, IDH-Wildtype2
  • Recurrent Glioblastoma2
  • Astrocytoma of Brain1

Other2 trials

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study
Phase 3
Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma
Phase 3

Birmingham, Alabama2 trials

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Children's Hospital of Alabama

Phase 3
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

University of Alabama at Birmingham

Phase 2/3

Phoenix, Arizona1 trial

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

Mayo Clinic Arizona

Phase 3

Sacramento, California1 trial

Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma

University of California Davis Comprehensive Cancer Center

Phase 1

San Francisco, California1 trial

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

University of California, San Francisco

San Antonio, Texas1 trial

Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma

Mays Cancer Center, UT Health San Antonio

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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