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Loncastuximab tesirine Clinical Trials
6 actively recruiting trials across 5 locations
▼ -1 trial since June 2026
Also known as: ADC ADCT-402, ADCT-402, Anti-CD19 PBD-conjugate ADCT-402, Lonca, Loncastuximab Tesirine-lpyl +5 more
Pipeline
Phase 1: 2Phase 2: 3Phase 2/3: 1
Top Sponsors
- ADC Therapeutics S.A.2
- University of Birmingham1
- M.D. Anderson Cancer Center1
- Juan P. Alderuccio, MD1
- City of Hope Medical Center1
Indications
- Cancer6
- B-Cell Non-Hodgkin Lymphoma2
- Relapsed B-Cell Non-Hodgkin Lymphoma1
- Refractory B-Cell Non-Hodgkin Lymphoma1
- Refractory Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma1
Other1 trial
Clovis, California1 trial
A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)
University of California San Francisco - Fresno Center for Medical Education and Research
Phase 1
Duarte, California1 trial
Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
City of Hope Medical Center
Phase 2
Lynwood, California1 trial
A Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or Refractory Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma With Hepatic Impairment (LOTIS-10)
The Oncology Institute of Hope & Innovation - Lynwood
Phase 1
Fort Myers, Florida1 trial
Loncastuximab Tesirine in Combination With Rituximab in Patients With Relapsed or Refractory Follicular Lymphoma
Florida Cancer Specialists and Research Institute
Phase 2
Houston, Texas1 trial
A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy
MD Anderson Cancer Center
Phase 2
Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.
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