Methadone Clinical Trials

3 actively recruiting trials across 3 locations

▲ +1 trial since May 2026

Pipeline

Early 1: 1Phase 2: 1Phase 4: 1

Top Sponsors

University of Virginia1
Mayo Clinic1
Johns Hopkins University1

Indications

Cancer3
Craniotomy Surgery1
Postoperative Care1
Postoperative1
Brain Injury1

Baltimore, Maryland1 trial

The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in Reducing Opioid Prescription.

The Johns Hopkins Bayview Medical Center

Phase 2

Rochester, Minnesota1 trial

Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing Surgery

Mayo Clinic in Rochester

Phase 4

Charlottesville, Virginia1 trial

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery

University of Virginia

Early 1

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.