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Ocrelizumab Clinical Trials

9 actively recruiting trials across 4 locations

▲ +1 trial since May 2026

Also known as: OCREVUS®, Ocrevus, RO4964913, RO4964913, Ocrevus, RO4964913; Ocrevus +1 more

Pipeline

Phase 2: 1Phase 3: 3Phase 4: 3

Top Sponsors

  • Hoffmann-La Roche4
  • Novartis Pharmaceuticals1
  • National Institute of Allergy and Infectious Diseases (NIAID)1
  • Johns Hopkins University1
  • Biogen1

Indications

  • Multiple Sclerosis9
  • Relapsing Multiple Sclerosis2
  • Primary Progressive Multiple Sclerosis1
  • Relapsing-remitting Multiple Sclerosis (RRMS)1
  • Progressive Multiple Sclerosis1

Other5 trials

A Study of the Efficacy and Safety of BCD-281 in Patients With Relapsing-Remitting Multiple Sclerosis
Phase 3
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis
Phase 4
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)
Phase 2
A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)
An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment
Phase 3

Scottsdale, Arizona1 trial

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Perseverance Research Center

Phase 3

New Haven, Connecticut1 trial

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Yale School of Medicine

Phase 4

Baltimore, Maryland1 trial

Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis

Johns Hopkins University

Phase 4

Eden Prairie, Minnesota1 trial

A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies

OptumInsight

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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