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Saruparib Clinical Trials

5 actively recruiting trials across 5 locations

▲ +1 trial since June 2026

Also known as: 2589531-76-8, AZD 5305, AZD-5305, AZD5305, PARP Inhibitor AZD5305

Pipeline

Early 1: 1Phase 2: 1Phase 3: 1Phase 1/2: 2

Top Sponsors

  • AstraZeneca3
  • SWOG Cancer Research Network1
  • OHSU Knight Cancer Institute1

Indications

  • Cancer5
  • Lung Cancer2
  • Locally Advanced Pancreatic Ductal Adenocarcinoma1
  • Lung Small Cell Carcinoma, P Subtype1
  • Lung Small Cell Carcinoma, N Subtype1

Phoenix, Arizona1 trial

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Research Site

Phase 3

Duarte, California1 trial

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Research Site

Phase 1/2

Loma Linda, California1 trial

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

Loma Linda University Medical Center

Phase 2

New York, New York1 trial

Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours

Research Site

Phase 1/2

Portland, Oregon1 trial

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

OHSU Knight Cancer Institute

Early 1

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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