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Telisotuzumab Adizutecan Clinical Trials

8 actively recruiting trials across 7 locations

▲ +1 trial since June 2026

Also known as: ABBV-400

Pipeline

Phase 1: 1Phase 2: 3Phase 3: 1Phase 1/2: 1Phase 2/3: 2

Top Sponsors

  • AbbVie8

Indications

  • Cancer8
  • Lung Cancer4
  • Colorectal Cancer2
  • Non Small Cell Lung Cancer2
  • Gastric/Esophageal Cancer1

Duarte, California2 trials

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

City of Hope National Medical Center /ID# 270255

Phase 2
Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

City of Hope National Medical Center /ID# 276272

Phase 1

Huntsville, Alabama1 trial

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

Clearview Cancer Institute - Huntsville - Cci Drive /ID# 278621

Phase 2

Chandler, Arizona1 trial

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Ironwood Cancer and Research Centers - Chandler II /ID# 275443

Phase 2/3

Phoenix, Arizona1 trial

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Mayo Clinic Hospital - Phoenix /ID# 272971

Phase 1/2

Springdale, Arkansas1 trial

A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Highlands Oncology Group - Springdale /ID# 277132

Phase 2/3

Beverly Hills, California1 trial

A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan

Beverly Hills Cancer Center /ID# 275465

Phase 2

East Brunswick, New Jersey1 trial

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

Astera Cancer Care /ID# 279532

Phase 3

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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