Tezepelumab Clinical Trials

8 actively recruiting trials across 4 locations

▲ +2 trials since July 2026

Also known as: MEDI9929 and AMG157, TEZSPIRE

Pipeline

Phase 2: 1Phase 3: 4Phase 4: 1

Top Sponsors

AstraZeneca5
University of Leeds1
University of Alberta1
Asger Sverrild1

Indications

Asthma5
Severe Asthma3
COPD3
Chronic Obstructive Pulmonary Disease (COPD)2
COPD Bronchitis1

Other4 trials

Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPD

Phase 2

Phase 3b Study in Patients With Severe Asthma Treated With Tezepelumab

Phase 3

Physical Activity Promotion and Clinical Remission in Severe Asthma

N/A

Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA)

Phase 4

Cullman, Alabama1 trial

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

Research Site

Phase 3

Foley, Alabama1 trial

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

Research Site

Phase 3

Montgomery, Alabama1 trial

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

Research Site

Phase 3

Wilmington, Delaware1 trial

Tezspire Cardiac Events PASS

Healthcare Integrated Research Database (HIRD)

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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