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Trifluridine-tipiracil Clinical Trials

13 actively recruiting trials across 5 locations

▼ -1 trial since May 2026

Also known as: (choose one combination) : oxalipatin or irinotecan, Bevacizumab, FTD/TPI, FTP/TPI, Irinotecan +3 more

Pipeline

Phase 1: 1Phase 2: 8Phase 3: 1Phase 1/2: 3

Top Sponsors

  • Sun Yat-sen University2
  • UNICANCER1
  • The Methodist Hospital Research Institute1
  • Regeneron Pharmaceuticals1
  • Qilu Hospital of Shandong University1

Indications

Other8 trials

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases
Phase 2
Efficacy and Safety of Trifluridine/Tipiracil Combined With Fufuquitinib for Third-line Treatment of mCRC
Phase 2
Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer
Phase 2
Regorafenib Combined With TAS-102 Versus Regorafenib Monotherapy in Third or Later Line Therapy of mCRC
Phase 2
Second-line Treatment of Metastatic Colorectal Cancer
Phase 2
Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy
Phase 2
Trifluridine/Tipiracil + Fruquintinib Versus Trifluridine/Tipiracil Alone for Metastatic Oeso-gastric Adenocarcinoma
Phase 3
ctDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC
Phase 1/2

Phoenix, Arizona1 trial

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Mayo Clinic

Phase 1/2

Scottsdale, Arizona1 trial

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

HonorHealth Research Institute

Phase 1

Los Angeles, California1 trial

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

Valkyrie Clinical Trials

Phase 1/2

Cleveland, Ohio1 trial

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

Phase 2

Houston, Texas1 trial

5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer

Houston Methodist Neal Cancer Center

Phase 2

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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