| Abatacept in Immune Checkpoint Inhibitor MyocarditisNCT05335928 · Los Angeles, California | Phase 3 | 29 |
| Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation TherapyNCT01696721 · Palo Alto, California | — | 24 |
| Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid LeukemiaNCT05237258 · Birmingham, Alabama | Not applicable | 20 |
| A Global Study of the PETAL ConsortiumNCT06067347 · Duarte, California | — | 10 |
| Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical TrialNCT03990896 · San Francisco, California | Phase 2 | 7 |
| Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in GoutNCT04875702 · South Birmingham, Alabama | Phase 4 | 7 |
| Developing a Test of Uterine Lavage for the Detection of Ovarian CancerNCT04794322 · Little Rock, Arkansas | — | 6 |
| Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TCNCT05668962 · Washington D.C., District of Columbia | Phase 2 | 6 |
| Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AFNCT06099730 · Jonesboro, Arkansas | Not applicable | 6 |
| Ivosidenib as Post-HSCT Maintenance for AMLNCT06707493 · Atlanta, Georgia | Phase 2 | 6 |
| Sacituzumab Govitecan In TNBCNCT04230109 · Boston, Massachusetts | Phase 2 | 5 |
| Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WMNCT06561347 · Denver, Colorado | Phase 2 | 5 |
| Ruxolitinib in Thrombocythemia and Polycythemia VeraNCT04644211 · Boston, Massachusetts | Phase 2 | 4 |
| Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot StudyNCT05524428 · Boston, Massachusetts | Not applicable | 4 |
| A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner CaregiversNCT06172907 · Boston, Massachusetts | Not applicable | 4 |
| Video Inspired Discussions About Ethical Outcomes in PediatricsNCT06786104 · Birmingham, Alabama | Not applicable | 4 |
| Identification and Treatment Of Micrometastatic Disease in Stage III Colon CancerNCT03803553 · Boston, Massachusetts | Phase 3 | 3 |
| ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant GliomasNCT03922555 · Boston, Massachusetts | Phase 1 | 3 |
| The HALT Biomarker StudyNCT04552275 · Boston, Massachusetts | Phase 1 | 3 |
| Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLLNCT04560322 · Boston, Massachusetts | Phase 2 | 3 |
| Folfox+Irinotecan+Chemort In Esophageal CancerNCT04656041 · Boston, Massachusetts | Phase 2 | 3 |
| I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm PatientsNCT05842603 · Boston, Massachusetts | Not applicable | 3 |
| Elranatamab in R/R Multiple MyelomaNCT06138275 · Boston, Massachusetts | Phase 2 | 3 |
| Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung CancerNCT06427954 · Los Angeles, California | Not applicable | 3 |
| BMT-CARE: Psychosocial Intervention for Transplant CaregiversNCT06472089 · Birmingham, Alabama | Not applicable | 3 |
| Novel Digital Application for Patients With Acute LeukemiaNCT06472128 · Boston, Massachusetts | Not applicable | 3 |
| Targeted Palliative Care Intervention for Patients With Metastatic Breast CancerNCT06795529 · Boston, Massachusetts | Not applicable | 3 |
| ELISA in Relapsed/Refractory MMNCT06832865 · Boston, Massachusetts | Phase 2 | 3 |
| Mezigdomide and Talquetamab in Relapsed and Refractory Multiple MyelomaNCT07032714 · Boston, Massachusetts | Phase 1 | 3 |
| Ivonescimab Alone And With Carboplatin/Pemetrexed For NSCLCNCT07405190 · Boston, Massachusetts | Phase 2 | 3 |
| DNA Analysis of Blood and Tissue from Patients with Lung CancerNCT00471978 · Boston, Massachusetts | — | 2 |
| Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast CancerNCT02290834 · Boston, Massachusetts | Not applicable | 2 |
| Palbociclib and Pembrolizumab In Central Nervous System MetastasesNCT02896335 · Boston, Massachusetts | Phase 2 | 2 |
| Buspirone and Melatonin for Depression Following Traumatic Brain InjuryNCT04400266 · Boston, Massachusetts | Phase 4 | 2 |
| HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver DiseaseNCT05205954 · Boston, Massachusetts | Not applicable | 2 |
| Genetic Testing Decision AidNCT05470920 · Boston, Massachusetts | Not applicable | 2 |
| Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's DiseaseNCT05776641 · Boston, Massachusetts | Not applicable | 2 |
| Lung Cancer Screening in High-risk Black IndividualsNCT05898594 · Chicago, Illinois | Not applicable | 2 |
| An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal CancerNCT05914766 · Boston, Massachusetts | Not applicable | 2 |
| Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple MyelomaNCT05922501 · Boston, Massachusetts | Phase 2 | 2 |
| Researching Heat and Yoga for Mood EnhancementNCT06094088 · Cambridge, Massachusetts | Not applicable | 2 |
| Ziftomenib Maintenance Post Allo-HCTNCT06440135 · Boston, Massachusetts | Phase 1 | 2 |
| Zanubrutinib, Obinutuzumab, Sonrotoclax (BOSon) or BGB-16673, Obinutuzumab, Sonrotoclax (DOSon) in TN CLL/SLLNCT06849713 · Boston, Massachusetts | Phase 2 | 2 |
| Flotufolastat F 18 PET in Men With Very Low PSA RecurrenceNCT06862856 · Boston, Massachusetts | — | 2 |
| Multidisciplinary Intervention for Adults With Chronic Graft-versus-host DiseaseNCT06910969 · Miami, Florida | Not applicable | 2 |
| Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEANCT07070466 · Santa Monica, California | Phase 2 | 2 |
| Finding Links Between Hot flASHes and CardioVascular DiseaseNCT07077395 · Boston, Massachusetts | Phase 2 | 2 |
| PDT For Induction Therapy For Head And Neck CancerNCT07214987 · Boston, Massachusetts | Phase 2 | 2 |
| Cardiac Effects of Mineralocorticoid Receptor Antagonism After PreeclampsiaNCT07238400 · Boston, Massachusetts | Phase 2 | 2 |
| Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant DepressionNCT07563868 · Boston, Massachusetts | Not applicable | 2 |
| Prospective Screening for Breast Cancer-related LymphedemaNCT01521741 · Boston, Massachusetts | — | 1 |
| A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in NewbornNCT01873131 · Boston, Massachusetts | Not applicable | 1 |
| Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing ProstatectomyNCT01961713 · Boston, Massachusetts | — | 1 |
| Phase II Study of Proton Radiation Therapy for NeuroblastomaNCT02112617 · Boston, Massachusetts | Not applicable | 1 |
| Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RTNCT02792270 · Boston, Massachusetts | Not applicable | 1 |
| Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging SystemNCT02947971 · Boston, Massachusetts | Not applicable | 1 |
| Diffusion MRI in Heart FailureNCT02973633 · Charlestown, Massachusetts | Early phase 1 | 1 |
| Turmeric for Patients With Basal Joint ArthritisNCT03017118 · Boston, Massachusetts | Not applicable | 1 |
| Molecular and Genetic Analysis of Lung CancerNCT03029325 · Boston, Massachusetts | — | 1 |
| Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation TherapyNCT03286335 · Boston, Massachusetts | Not applicable | 1 |
| Biomechanical Precision Medicine Registry for Patients With and Without Heart FailureNCT03480633 · Boston, Massachusetts | — | 1 |
| Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis PatientsNCT03535545 · Boston, Massachusetts | Phase 1 | 1 |
| Imaging Histone Deacetylase in the HeartNCT03549559 · Boston, Massachusetts | Not applicable | 1 |
| Positron Emission Tomography (PET) Imaging of ThrombosisNCT03830320 · Boston, Massachusetts | Phase 1 | 1 |
| Pilot Study for OCT Guided In Vivo Laser Capture Microdissection for Assessing the Prognosis of Barrett's EsophagusNCT03830801 · Boston, Massachusetts | Not applicable | 1 |
| Use of BMAC With Hip Arthroscopy Treatment of FAI and Labral TearNCT03909139 · Boston, Massachusetts | — | 1 |
| Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric PopulationsNCT04296604 · Boston, Massachusetts | Not applicable | 1 |
| Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue InjuryNCT04485286 · Boston, Massachusetts | Phase 2 | 1 |
| Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind StudyNCT04496947 · Boston, Massachusetts | Not applicable | 1 |
| The Effect of Mindfulness on Vascular Inflammation in Stable Coronary DiseaseNCT04505865 · Boston, Massachusetts | Not applicable | 1 |
| Oxytocin for Weight Loss in AdolescentsNCT04551482 · Boston, Massachusetts | Phase 2 | 1 |
| Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis SubjectsNCT04699747 · Boston, Massachusetts | Phase 1 | 1 |
| Intraoperative Tumor Margin Identification With ICG Dye ImagingNCT04752137 · Boston, Massachusetts | Phase 2 | 1 |
| Promoting Well-being and Health in Heart FailureNCT04829617 · Boston, Massachusetts | Not applicable | 1 |
| Estrogen Administration for the Treatment of NASH in Postmenopausal WomenNCT04833140 · Boston, Massachusetts | Phase 3 | 1 |
| IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis FracturesNCT04842266 · Boston, Massachusetts | — | 1 |
| Intermittent Fasting for NAFLD in AdultsNCT04899102 · Boston, Massachusetts | Not applicable | 1 |
| Patient-centered, Optimal Integration of Survivorship and Palliative CareNCT04900935 · Boston, Massachusetts | Not applicable | 1 |
| Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic SurgeryNCT04912531 · Boston, Massachusetts | Not applicable | 1 |
| NTS-WBRT in Brain MetastasesNCT05013892 · Boston, Massachusetts | Phase 2 | 1 |
| Cannabidiol for Reduction of Brain NeuroinflammationNCT05066308 · Boston, Massachusetts | Phase 2 | 1 |
| Prostate Cancer Genetic Risk Evaluation and Screening StudyNCT05129605 · Boston, Massachusetts | — | 1 |
| Screening For BCRL In Targeted Therapy For Breast CancerNCT05142800 · Boston, Massachusetts | — | 1 |
| Assess Fibrin in Brains With AD/ADRDNCT05336695 · Boston, Massachusetts | Phase 1/2 | 1 |
| Peripheral Neuroimmune Mechanisms of HyperthermiaNCT05366270 · Boston, Massachusetts | Not applicable | 1 |
| Positive Emotions Following Acute Cardiac EventsNCT05412862 · Boston, Massachusetts | Not applicable | 1 |
| Boosting Emotional Well-being and Happiness in Outpatients Living With DiabetesNCT05420051 · Boston, Massachusetts | Not applicable | 1 |
| Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With DepressionNCT05450432 · Boston, Massachusetts | Phase 4 | 1 |
| Targeting Specific Brain Networks to Treat Specific Symptoms in DepressionNCT05523817 · Boston, Massachusetts | Not applicable | 1 |
| Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIVNCT05570812 · Boston, Massachusetts | Phase 2 | 1 |
| Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEFNCT05577819 · Boston, Massachusetts | Not applicable | 1 |
| Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular TherapyNCT05646576 · Boston, Massachusetts | Not applicable | 1 |
| Training in Evidence-based Treatments in Psycho-OncologyNCT05674357 · Boston, Massachusetts | Not applicable | 1 |
| Screening Trial for Pain Relief in Schwannomatosis (STARFISH)NCT05684692 · Boston, Massachusetts | Phase 2 | 1 |
| COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCERNCT05692024 · Boston, Massachusetts | Phase 1/2 | 1 |
| Cryoablation+Ipilimumab+Nivolumab in MelanomaNCT05779423 · Boston, Massachusetts | Phase 2 | 1 |
| Health Opportunities and Promoters of Equitable Screening for Lung CancerNCT05784922 · Boston, Massachusetts | — | 1 |
| Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income PopulationNCT05799222 · Boston, Massachusetts | — | 1 |
| Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OANCT05839535 · Charlestown, Massachusetts | Phase 2 | 1 |
| Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical ADNCT05881239 · Boston, Massachusetts | — | 1 |
| Supplemental Oxygen in Pulmonary Embolism (SO-PE)NCT05891886 · Boston, Massachusetts | Early phase 1 | 1 |
| Individual Closed-Loop Neuromodulation Therapy for Alzheimer's DiseaseNCT05904132 · Charlestown, Massachusetts | Not applicable | 1 |
| Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental IllnessNCT05962879 · Boston, Massachusetts | Not applicable | 1 |
| NeuroPathways Intervention for Brain Tumor PatientsNCT05976490 · Boston, Massachusetts | Not applicable | 1 |
| LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver DiseaseNCT05998330 · Boston, Massachusetts | Not applicable | 1 |
| Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral PathologiesNCT06003101 · Boston, Massachusetts | Phase 3 | 1 |
| GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGHNCT06003153 · Boston, Massachusetts | Phase 4 | 1 |
| PET Imaging Evaluation of [11C]SY08NCT06098612 · Charlestown, Massachusetts | Early phase 1 | 1 |
| ASCENT Intervention for Brain Tumor PatientsNCT06099743 · Boston, Massachusetts | Not applicable | 1 |
| Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via InfliximabNCT06136546 · Boston, Massachusetts | Phase 2 | 1 |
| Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver CirrhosisNCT06265272 · Charlestown, Massachusetts | — | 1 |
| Pemigatinib + Afatinib in Advanced Refractory Solid TumorsNCT06302621 · Boston, Massachusetts | Phase 1 | 1 |
| EVOC - EVs in Obesity and Cardiometabolic DiseaseNCT06408961 · Boston, Massachusetts | — | 1 |
| The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)NCT06412172 · New Haven, Connecticut | — | 1 |
| Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONlineNCT06432790 · Boston, Massachusetts | Not applicable | 1 |
| Initial Resuscitation for Acute Kidney Injury in CirrhosisNCT06525623 · Boston, Massachusetts | Not applicable | 1 |
| Transcranial Magnetic Stimulation Treatment for Alzheimer's DiseaseNCT06538311 · Boston, Massachusetts | Early phase 1 | 1 |
| Psychoeducational Intervention for Patients With Hepatocellular CarcinomaNCT06541990 · Boston, Massachusetts | Not applicable | 1 |
| Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic ConditionsNCT06557005 · Boston, Massachusetts | Not applicable | 1 |
| Cannabis, Linked Emotions, and Adolescent Risk StudyNCT06576076 · Boston, Massachusetts | Not applicable | 1 |
| G-CSF After Chemo-radiation in Patients With GlioblastomaNCT06649851 · Boston, Massachusetts | Phase 2 | 1 |
| SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) TrialNCT06674109 · Boston, Massachusetts | Phase 4 | 1 |
| Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell TransplantationNCT06676852 · Boston, Massachusetts | Not applicable | 1 |
| CRC Screening in Unscreened Individuals 45-54NCT06757192 · Boston, Massachusetts | — | 1 |
| Positive Fit to Colonoscopy: Closing the GapNCT06763432 · Boston, Massachusetts | — | 1 |
| Efficacy of Synchronous, Virtual Cognitive Behavioral Therapy for Insomnia Across Phases of Cancer SurvivorshipNCT06807086 · Boston, Massachusetts | Not applicable | 1 |
| Improving Coronary Vascular Health in WomenNCT06843902 · Boston, Massachusetts | Phase 2 | 1 |
| Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis UseNCT06878859 · Boston, Massachusetts | Not applicable | 1 |
| Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CTNCT06910956 · Boston, Massachusetts | Not applicable | 1 |
| Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve CapNCT06915662 · Boston, Massachusetts | Phase 2 | 1 |
| A Preventive Behavioral Intervention for Young Adults With Psychotic ExperiencesNCT06929442 · Charlestown, Massachusetts | Not applicable | 1 |
| TMS for Cognitive Decline in Aging and Preclinical ADNCT06956300 · Boston, Massachusetts | Not applicable | 1 |
| Increasing Resiliency Among Early Post-Treatment Lymphoma SurvivorsNCT07014293 · Boston, Massachusetts | Not applicable | 1 |
| Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for DepressionNCT07082998 · Boston, Massachusetts | Not applicable | 1 |
| Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular HealthNCT07087431 · Boston, Massachusetts | Not applicable | 1 |
| Building ConnectionsNCT07091032 · Boston, Massachusetts | Not applicable | 1 |
| Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal TumorsNCT07095517 · Boston, Massachusetts | Phase 1 | 1 |
| ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early AdolescenceNCT07102797 · Somerville, Massachusetts | Not applicable | 1 |
| Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus StudyNCT07118722 · Boston, Massachusetts | Not applicable | 1 |
| Botensilimab, Balstilimab, and SBRT in Colorectal CancerNCT07128355 · Boston, Massachusetts | Early phase 1 | 1 |
| Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac ArrestNCT07143357 · Boston, Massachusetts | Not applicable | 1 |
| Online Parent Education for Child AnxietyNCT07153250 · Boston, Massachusetts | Not applicable | 1 |
| BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer PreventionNCT07162337 · Boston, Massachusetts | Not applicable | 1 |
| 45th Multicenter Airway Research CollaborationNCT07166939 · Cleveland, Ohio | Phase 4 | 1 |
| Time Restricted Eating (TRE) in Bipolar DisorderNCT07211217 · Boston, Massachusetts | Not applicable | 1 |
| A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE CapsuleNCT07219537 · Boston, Massachusetts | Not applicable | 1 |
| Behavioral Health Program for Short-Stay Nursing Facility Residents & Care PartnersNCT07220486 · Boston, Massachusetts | Not applicable | 1 |
| Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist TreatmentNCT07226947 · Boston, Massachusetts | Not applicable | 1 |
| A Digital Health Intervention to Improve Physical Function and Wellness of Lung Cancer SurvivorsNCT07227623 · Boston, Massachusetts | Not applicable | 1 |
| Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health LiteracyNCT07233408 · Boston, Massachusetts | Not applicable | 1 |
| Biomarker-based Trial of NPC-1 for Alzheimer's PathologyNCT07236190 · Boston, Massachusetts | Phase 2 | 1 |
| Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout FlaresNCT07346079 · Boston, Massachusetts | Phase 4 | 1 |
| Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and HospitalNCT07359157 · Worcester, Massachusetts | Not applicable | 1 |
| Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the LiverNCT07364474 · Boston, Massachusetts | Not applicable | 1 |
| A Nurse-Led, Coping and Supportive Intervention for Patients With Triple-Negative Breast CancerNCT07513311 · Boston, Massachusetts | Not applicable | 1 |
| Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary DiseaseNCT07568509 · Boston, Massachusetts | Early phase 1 | 1 |
| Pilot Study of a Behavioral Program for Resident Depression in Skilled Nursing FacilitiesNCT07655232 · Boston, Massachusetts | Not applicable | 1 |
| Addressing Cancer Care Equity With Social Determinants of Health Screening and Early InterventionNCT07671209 · Boston, Massachusetts | Not applicable | 1 |