Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis

Summary

The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthritis.

Eligibility

Inclusion Criteria:

* Men and women 18 years of age or older can participate in this study.
* Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study.
* Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis.

Exclusion Criteria:

* Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.
* Pregnant patients.
* Patients who is claustrophobic.
* Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc.
* Patients with shock hypotension or unstable low blood pressure.
* Patients with Rhabdomyolysis.
* Patients who have had a contrast enhanced (with gadolinium) MRA (magnetic resonance angiography)/ or MRI within the last 3 months. (Contrast is a medication injected into a vein during a imaging examination that helps produce clearer images/pictures).

Conditions2

Locations1 site

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