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Mechanisms Underlying Impaired Diabetic Wound Healing

RECRUITINGSponsored by University of Pittsburgh
Actively Recruiting
SponsorUniversity of Pittsburgh
Started2008-09-01
Est. completion2029-12-31
Eligibility
Age21 Years – 80 Years
Healthy vol.Accepted
Locations5 sites
View on ClinicalTrials.gov →

NCT00777712

Summary

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.

Eligibility

Age: 21 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Ages 21-80
* Chronic Wound (present \>4 weeks)
* Diabetic \& Non-diabetic
* Adult surgical wounds

Exclusion Criteria:

* Inability to consent
* Pregnant women
* Therapeutically immunocompromised
* Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9

Conditions2

DiabetesNon-healing Wounds

Locations5 sites

Indiana

1 site
Comprehensive Wound Care Centers
Indianapolis, Indiana, 46202

Ohio

1 site
Comprehensive Wound Care Centers
Columbus, Ohio, 43210

Pennsylvania

3 sites
University of Pittsburgh - McKeesport
Pittsburgh, Pennsylvania, 15132
Josephine Vidic, BS412-624-0422jbv9@pitt.edu
University of Pittsburgh - Mercy
Pittsburgh, Pennsylvania, 15219
Josephine Vidic, BS412-624-0422jbv9@pitt.edu
University of Pittsburgh - Passavant
Pittsburgh, Pennsylvania, 16066
Josephine Vidic, BS412-624-0422jbv9@pitt.edu

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