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Mechanisms Underlying Impaired Diabetic Wound Healing

RECRUITINGSponsored by University of Pittsburgh
Actively Recruiting
SponsorUniversity of Pittsburgh
Started2008-09-01
Est. completion2029-12-31
Eligibility
Age21 Years – 80 Years
Healthy vol.Accepted
Locations2 sites
View on ClinicalTrials.gov →

NCT00777712

Summary

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.

Eligibility

Age: 21 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Ages 21-80
* Chronic Wound (present \>4 weeks)
* Diabetic \& Non-diabetic
* Adult surgical wounds

Exclusion Criteria:

* Inability to consent
* Pregnant women
* Therapeutically immunocompromised
* Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9

Conditions3

DiabetesNon-healing WoundNon-healing Wounds

Locations2 sites

UPMC Montefiore
Pittsburgh, Pennsylvania, 15219
CeCe Zamarripa, RN412-647-7728zamarripaca@upmc.edu
UPMC Presbyterian
Pittsburgh, Pennsylvania, 15219
Cecilia Zamarripa, RN412-647-7728zamarripaca@upmc.edu

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