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Pancreatic Cancer Genetics

RECRUITINGSponsored by Columbia University
Actively Recruiting
SponsorColumbia University
Started2008-01
Est. completion2026-12
Eligibility
Age18 Years – 85 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT01102569

Summary

The aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relatives of hereditary pancreatic cancer patients may have a significant impact; allowing for early screening, treatment, and resection of pre-malignant tissue or malignant lesions.

Eligibility

Age: 18 Years – 85 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients diagnosed with pancreatic cancer.
* Patients are of Ashkenazi Jewish descent.
* Patients have been Columbia Pancreatic Cancer Prevention Program Registry and Tissue Bank for High-Risk Individuals (IRB-AAAA6154).

Exclusion Criteria:

* Inability to provide informed consent.
* Under the age of 18 years old.

Conditions3

Breast CancerCancerPancreatic Cancer

Locations1 site

Columbia University Medical Center
New York, New York, 10032
Fay Kastrinos, MD212-305-1021fk18@columbia.edu

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