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Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

RECRUITINGSponsored by Children's National Research Institute
Actively Recruiting
SponsorChildren's National Research Institute
Started2010-04
Est. completion2025-04
Eligibility
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT01106794

Summary

The purpose of this study is to prospectively collect specimens from pediatric patients with diffuse intrinsic pontine glioma or brainstem glioma, either during therapy or at autopsy, in order to characterize the molecular abnormalities of this tumor.

Eligibility

Healthy volunteers accepted
Inclusion Criteria:

* Patients of any age with clinical and radiologic diagnosis of diffuse intrinsic pontine glioma
* Patients with other high-grade gliomas originating in the brainstem
* Patients with focal gliomas (WHO grade I/II) of the brainstem

Exclusion Criteria:

* Patients with any type of infiltrative low grade (WHO grade I and II) or high grade glioma (WHO grade III and IV) originating outside the brainstem
* Patients harboring primary brainstem tumors with other histologic diagnoses (e.g., PNET)

Conditions3

Brainstem GliomaCancerDiffuse Intrinsic Pontine Glioma

Locations1 site

Children's National Medical Center
Washington D.C., District of Columbia, 20010
Javad Nazarian, PhD

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