|

Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study

RECRUITINGSponsored by Brigham and Women's Hospital
Actively Recruiting
SponsorBrigham and Women's Hospital
Started1994-07
Est. completion2027-07
Eligibility
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT01177618

Summary

Chronic obstructive pulmonary disease (COPD) is often caused by cigarette smoking, but genetic predisposition also influences COPD susceptibility. The purpose of this study is to identify genetic factors that predispose some individuals to develop COPD.

Eligibility

Healthy volunteers accepted
Inclusion Criteria for Early-Onset COPD Probands:

* Early onset of COPD in individuals younger than 53 years old
* Spirometry results that are indicative of severe COPD (FEV1 \< 40% predicted)
* Physician-diagnosed COPD

Exclusion Criteria for Early-Onset COPD Probands:

* Severe alpha-1 antitrypsin deficiency
* Other chronic lung diseases in participants with COPD (except asthma)
* Pregnant
* Any previous lung surgery including lung transplant or lung reduction volume surgery (LVRS); unless prior Pulmonary Function Tests are available

Conditions2

COPDChronic Obstructive Pulmonary Disease

Locations1 site

Brigham and Women's Hospital
Boston, Massachusetts, 02115
Edwin Silverman617-525-0856ed.silverman@channing.harvard.edu

Browse More Trials

COPD trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.