Cryopreservation of Ovarian Tissue

Summary

The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.

Eligibility

Inclusion Criteria:

* Females 0-45 years of age who are premenopausal
* Treatment plan that will likely result in premature menopause or premature ovarian failure
* This includes patients receiving:
* Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy
* Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients
* Patient is unable or unwilling to pursue fertility preservation by freezing oocytes or embryos.
* Previous treatment for cancer is acceptable if patient still has ovarian function
* Patient is medically stable enough to undergo surgery (cleared for anesthesia)

Exclusion Criteria:

* Patients not meeting the above criteria
* Patients who have not received medical clearance from their physicians to undergo surgery
* Patients already experiencing menopause.

Conditions3

Locations1 site

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