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Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia

RECRUITINGSponsored by University Hospital, Basel, Switzerland
Actively Recruiting
SponsorUniversity Hospital, Basel, Switzerland
Started2004-05
Est. completion2025-12
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT01838148

Summary

The primary aim is to perform the largest study worldwide to evaluate novel biochemical and electrocardiographic signatures alone as well as in combination with the standard 12-lead exercise ECG in the detection of exercise-induced myocardial ischemia (diagnostic endpoint). The secondary aim is to evaluate these innovative tools in the risk prediction for the occurrence of cardiovascular death and acute myocardial infarction during long-term follow-up.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients presenting with suspected exercise-induced myocardial ischemia referred for rest/ergometry myocardial perfusion SPECT

Exclusion Criteria:

* Age \< 18 years
* Pregnancy
* Unable or unwilling to give informed consent
* Symptoms at rest or minor exertion

Conditions6

Angina (Stable)Biological MarkersCoronary Artery DiseaseExercise TestHeart DiseaseSPECT

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