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The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

RECRUITINGSponsored by Abramson Cancer Center at Penn Medicine
Actively Recruiting
SponsorAbramson Cancer Center at Penn Medicine
Started2009-01
Est. completion2026-01
Eligibility
Age18 Years – 100 Years
Healthy vol.Accepted
Locations1 site

Summary

Retrospective studies indicate that active surveillance for clinically localized, small renal masses (cT1a, \<=4cm) is safe. It is our hypothesis that active surveillance is safe and efficacious when compared prospectively to patients undergoing immediate intervention for their small renal mass.

Eligibility

Age: 18 Years – 100 YearsHealthy volunteers accepted
Inclusion Criteria:

* Must have a solid, enhancing renal mass ≤4cm at its greatest dimension found on incidental scanning in the last 6 months.
* Age ≥ 18 and able to read, understand and sign informed consent.
* Must be willing to adhere to the treatment algorithm and time constraints therein.

Exclusion Criteria:

* Cannot have suspicion of metastases to the kidney if any other malignancy diagnosed within two years of study entry.

Conditions2

CancerKidney Neoplasm

Locations1 site

Johns Hopkins Hospital
Baltimore, Maryland, 21287
Phillip M Pierorazio, MD410-502-5984philpierorazio@jhmi.edu

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