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Studies of Neuregulin/ERBB Signaling in Human Heart

RECRUITINGSponsored by Douglas B. Sawyer
Actively Recruiting
SponsorDouglas B. Sawyer
Started2015-06
Est. completion2028-09
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT02820233

Summary

This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Clinical diagnosis of severe coronary artery disease scheduled to undergo coronary artery bypass surgery.

Exclusion Criteria:

* less than 18 years of age
* unwilling or unable to provide informed consent
* known active myocarditis
* hypertrophic cardiomyopathy
* constrictive pericarditis or other significant pericardial disease
* severe pulmonary hypertension
* significant renal impairment (Cr \> 2.5 mg/dL)
* severe ventricular arrhythmias
* pregnancy

Conditions3

Heart DiseaseHeart FailureVascular Disease

Locations1 site

Maine Medical Center
Portland, Maine, 04102
Joanne Burgess, RN207-662-2414BURGEJS@mmc.org

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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