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Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer

RECRUITINGN/ASponsored by The First Affiliated Hospital of Henan University of Science and Technology
Actively Recruiting
PhaseN/A
SponsorThe First Affiliated Hospital of Henan University of Science and Technology
Started2016-11
Est. completion2025-12
Eligibility
Age18 Years – 75 Years
Healthy vol.Accepted

Summary

The aim of this study is to compare outcomes in Chinese patients with locally advanced resectable esophageal squamous cell cancer who have received either surgery or definitive chemoradiation (CRT) by the randomized, open-label, multicenter trial.

Eligibility

Age: 18 Years – 75 YearsHealthy volunteers accepted
Inclusion Criteria:

* Chinese
* esophageal squamous cell cancer
* mid or lower esophageal cancer
* tumor is resectable disease
* clinical stage: cT1bN+Mo, or cT2-4aN0-2M0

Exclusion Criteria:

* who had distant metastasis to solid visceral organs or local invasion into trachea, descending aorta, or recurrent laryngeal nerve.
* who had a serious premorbid condition or a poor physical status that compromised a thoracotomy.

Conditions2

CancerEsophagus Cancer

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