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Early Rheumatoid Arthritis Lung Disease Study

RECRUITINGSponsored by University of Nebraska
Actively Recruiting
SponsorUniversity of Nebraska
Started2017-03-31
Est. completion2028-03
Eligibility
Age19 Years – 90 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT03192267

Summary

Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.

Eligibility

Age: 19 Years – 90 YearsHealthy volunteers accepted
Inclusion Criteria:

* 19-90 years of age
* Able to give informed consent
* Diagnosis of RA by a Rheumatologist using 2010 American College of Rheumatology (ACR) criteria within the past 2 years

Exclusion Criteria:

* Inflammatory arthritis that does not meet 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA)
* Pregnant

Conditions2

ArthritisRheumatoid Arthritis

Locations1 site

University of Nebraska Medical Center
Omaha, Nebraska, 68198
Aimee B Schreiner, MS402-559-4873aischreiner@unmc.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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