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Berlin-Brandenburg Pregnancy Cohort

RECRUITINGSponsored by Charite University, Berlin, Germany
Actively Recruiting
SponsorCharite University, Berlin, Germany
Started2017-09-26
Est. completion2027-10
Eligibility
Age18 Years – 45 Years
SexFEMALE
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT03313024

Summary

This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

Eligibility

Age: 18 Years – 45 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* healthy pregnant women after giving informed consent
* pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes

Exclusion Criteria:

* infections
* alcohol and drug abuse
* manifest and chronic diseases

Conditions4

DiabetesDiabetes Mellitus in PregnancyPreeclampsiaPregnancy Complications

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