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Target Therapies Resistance Molecular Profiling in Patients With Neoplastic Disease

RECRUITINGSponsored by Fondazione del Piemonte per l'Oncologia
Actively Recruiting
SponsorFondazione del Piemonte per l'Oncologia
Started2011-03-30
Est. completion2026-03-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT03347318

Summary

The main purpose of this study is to define the molecular profile of selected solid tumors. From each participants will be collected biological materials for molecular analysis, including saliva, blood and vital tumor tissue derived form surgical or biopsy procedures. Whereas possible, vital tumor specimens will be inoculated and propagated in immunocompromised NOD/SCID mice to study the genetic correlations between genetic status and response to target drugs.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

Patients with at least one of the following selected solid tumors:

* Colorectal Cancer (primary or with synchronous/metachronous liver metastases)
* Prostate Cancer
* Head \& Neck Tumors
* Gastric Cancer
* Glioblastoma
* Breast Cancer
* Hepatocarcinoma
* Biliary Tract Carcinoma
* Lung Cancer (primary)
* Rare Tumors (incidence ≤ 5x10-6)
* Metastatic Sarcoma
* Metastatic Melanoma

Exclusion Criteria:

\-

Conditions2

CancerSolid Tumors

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