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Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates

RECRUITINGN/ASponsored by University of Calgary
Actively Recruiting
PhaseN/A
SponsorUniversity of Calgary
Started2018-01-01
Est. completion2027-01-01
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT03446326

Summary

The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.

Eligibility

Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* Age 18-70 years (inclusive)
* Implanted permanent pacemaker or implanted defibrillator capable of atrial and ventricular pacing
* LV ejection fraction \>50%

Exclusion Criteria:

* Unable or unwilling to provide informed consent
* Clinical need for a cardiac resynchronization device

Conditions2

Heart DiseaseVasovagal Syncope

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