Genetics Of Autoimmunity In Type I Diabetes

Summary

The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.

Eligibility

Inclusion Criteria (Families):

* Families where at least one first-degree family member has type 1 diabetes
* The diabetic proband in the family was diagnosed before the age of 39
* Family members must be at least 2 years old to participate

Exclusion Criteria (Families):

* Families with no history of type 1 diabetes
* Families with a history of diabetes that is not type 1 (LADA, MODY, type 2 etc.)

Inclusion Criteria (Controls):

* No family history of type 1 diabetes or other autoimmune conditions
* Age 2 or older

Exclusion Criteria (Controls):

* Personal or family history of autoimmune disease

Conditions5

Locations1 site

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