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Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

RECRUITINGSponsored by Alzheimer's Light LLC
Actively Recruiting
SponsorAlzheimer's Light LLC
Started2018-01-01
Est. completion2029-12-31
Eligibility
Age50 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT03657745

Summary

Electrical activity in the brain known as "gamma" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per second or 40Hz increased gamma brainwaves and led to clearing of beta amyloid plaques in the brain, a key abnormality in Alzheimer's disease. This project will test the ability of a novel iPad App (AlzLife https://www.alz.life/) that delivers light therapy at 40 Hz combined with cognitive therapy to improve cognition, function, and quality of life in Alzheimer's disease.

Eligibility

Age: 50 Years+Healthy volunteers accepted
Inclusion Criteria:

* Alzheimer's disease
* Cognitive Impairment

Exclusion Criteria:

* any previously noted epileptic seizures, including febrile seizures.
* any significant disease of the eye, such as macular degeneration. Since the 40Hz light therapy is delivered via eye stimulation, healthy eyes are required.

Conditions7

Alzheimer DiseaseAlzheimer's DiseaseCognition Disorders in Old AgeCognitive DeclineCognitive DeteriorationDementiaMild Cognitive Impairment

Locations1 site

Andrey Vyshedskiy
Miami, Florida, 33156
Andrey Vyshedskiy617-433-8577vysha@bu.edu

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