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Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

RECRUITINGSponsored by City of Hope Medical Center
Actively Recruiting
SponsorCity of Hope Medical Center
Started2026-04-25
Est. completion2028-09-25
Eligibility
Age19 Years+
Healthy vol.Accepted
Locations1 site

Summary

This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules. Using diagnostic testing, such as the diagnostic DNA methylation signature, may be a less invasive way to check for thyroid cancer.

Eligibility

Age: 19 Years+Healthy volunteers accepted
Inclusion Criteria:

* All patients undergoing FNA for thyroid nodule diagnosis.
* Any race and ethnicity are eligible for the study.
* Patient should have thyroid nodule(s) with indeterminate diagnosis after FNA (Bethesda category of indeterminate FNA \[III-V\]).

Conditions2

CancerThyroid Gland Nodule

Locations1 site

City of Hope Medical Center
Duarte, California, 91010
Maria Hahn, PhD626-256-4673mhahn@coh.org

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