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Pencil Beam Scanning in Patients With Renal Tumors

RECRUITINGEarly 1Sponsored by Children's Hospital of Philadelphia
Actively Recruiting
PhaseEarly 1
SponsorChildren's Hospital of Philadelphia
Started2017-12-26
Est. completion2026-10-30
Eligibility
Age0 Years – 30 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT03810651

Summary

This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.

Eligibility

Age: 0 Years – 30 YearsHealthy volunteers accepted
Inclusion Criteria:

* Less than 30 years of age
* Diagnosis

  a. Any patient with Wilms tumor or clear cell sarcoma of the kidney who would require radiation therapy as standard of care including
  1. Any patient with favorable histology (FH), stage III disease
  2. Any patient with focal or diffuse anaplasia
  3. Any patient with CCSK
* The patient is a candidate for external beam radiotherapy based on standard of care for treatment of Wilms tumor or CCSK

Exclusion Criteria:

* Prior radiotherapy to the region of the study cancer
* Chemotherapy administered for diagnosis of Wilms tumor or CCSK
* Pregnant or breastfeeding

Conditions3

CancerRenal TumorWilms Tumor

Locations1 site

Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104
Christine Hill-Kayser, MD215-590-2810hill@uphs.upenn.edu

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