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Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

RECRUITINGPhase 4Sponsored by Mayo Clinic
Actively Recruiting
PhasePhase 4
SponsorMayo Clinic
Started2019-06-27
Est. completion2030-05
Eligibility
Age60 Years+
SexFEMALE
Healthy vol.Accepted
Locations2 sites

Summary

The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.

Eligibility

Age: 60 Years+Sex: FEMALEHealthy volunteers accepted
Mayo Clinic Rochester-

Inclusion Criteria:

* Women who previously participated in this study
* Currently aged 60 years and older
* More than six months post chemotherapy or major surgery requiring general anesthesia
* Willing and able to sign informed consent

Exclusion Criteria:

* Not able to read and speak English
* In hospice
* Claustrophobic
* If undergoing Tau imaging, cannot have QT Prolongation

Mayo Clinic Jacksonville-

Inclusion Criteria:

* African American Women
* Currently aged 60 years and older
* More than six months post chemotherapy or major surgery requiring general anesthesia
* Willing and able to sign informed consent

Exclusion Criteria:

* Not able to read and speak English
* In hospice
* Claustrophobic
* If undergoing Tau imaging, cannot have QT Prolongation

Conditions2

Alzheimer DiseaseAlzheimer's Disease

Locations2 sites

Florida

1 site
Mayo Clinic
Jacksonville, Florida, 32224
Twilla Morrell, CRC904-953-3420morrell.twila@mayo.edu

Minnesota

1 site
Mayo Clinic
Rochester, Minnesota, 55905

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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