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Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention

RECRUITINGN/ASponsored by Chinese University of Hong Kong
Actively Recruiting
PhaseN/A
SponsorChinese University of Hong Kong
Started2019-04-01
Est. completion2025-12-31
Eligibility
Age18 Years – 65 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT03875625

Summary

The study is aimed * To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery. * To test the hypothesis that Brown fat is an independent biomarker for the development of Non Alcoholic Fat Liver Disease (NAFLD) * To study the association among Brown fat, NAFLD and obesity.

Eligibility

Age: 18 Years – 65 YearsHealthy volunteers accepted
Inclusion Criteria:

* BMI ≥ 25-30 kg/m2
* BMI ≥ 30 kg/m2 with Metabolic syndrome
* BMI ≥ 35 kg/m2 for morbid obesity

Exclusion Criteria:

* Other kind of hepatic diseases
* Under medications known to affect liver fat
* Waist circumference ≥ 150 cm
* Weight ≥ 250 kg
* MRI contraindications

Conditions9

Abdominal Subcutaneous FatBrown FatDiabetesDiabetes MellitusInsulin ResistanceLiver DiseaseMetabolic DiseaseNon Alcoholic Fatty Liver DiseaseObesity, Morbid

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