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Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool?

RECRUITINGN/ASponsored by French Cardiology Society
Actively Recruiting
PhaseN/A
SponsorFrench Cardiology Society
Started2020-01-24
Est. completion2025-12-31
Eligibility
Age60 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT03895541

Summary

The new approach propose in this protocol is based on ultrafast ultrasound and remote palpation of tissue by ultrasonic radiation pressure. Ultrafast ultrasound of biological tissues is based on an innovative ultrasound imaging approach that can image very fast soft tissue events at a rate of several thousands of frames per second and provide quantitative mapping of the elasticity of the tissues. This current project aims is to focus on myocardial rigidity in diastole to better assess the function of the heart failure.

Eligibility

Age: 60 Years – 80 YearsHealthy volunteers accepted
Global Inclusion Criteria:

* Hospitalization in cardiology services for acute pulmonary edema during heart failure
* Natriuretic peptide type B ≥35 pg/ml
* Echocardiographic structural alteration

Specific Inclusion criteria

* Group "preserved LVEF": Left ventricular Ejection Fraction ≥50%
* Group "moderate alteration of LVEF": Left ventricular Ejection Fraction between 40% and 49%
* Group "Systolic heart failure": Left ventricular Ejection Fraction\< 40%

Global Exclusion Criteria:

* Other associated lung pathology
* Other heart disease
* Contraindication to MRI or echocardiography gel
* Pregnancy
* Poor echogenicity,

Conditions2

Cardiovascular Diseases in Old AgeHeart Disease

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