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Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

RECRUITINGSponsored by University of Southern California
Actively Recruiting
SponsorUniversity of Southern California
Started2018-04-12
Est. completion2026-05-15
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

This research trial studies characterization of T-cell repertoire through next-generation sequencing in patients with acute myeloid leukemia undergoing stem cell transplant. Characterizing T-cell repertoire may help to understand if immune system plays a significant role in high risk patients with acute myeloid leukemia.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Diagnosis of AML scheduled to undergo HSCT at University of Southern California (USC)

Exclusion Criteria:

* Inability to provide consent because of severe mental disorders
* Donor unwilling to provide consent

Conditions2

Acute Myeloid LeukemiaCancer

Locations1 site

USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033
Houda Alachkar323-442-2696alachkar@usc.edu

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