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Molecular Basis of Pediatric Liver Cancer

RECRUITINGSponsored by University of Pittsburgh
Actively Recruiting
SponsorUniversity of Pittsburgh
Started2015-06-22
Est. completion2028-06-30
Eligibility
Age0 Years – 99 Years
Healthy vol.Accepted
Locations1 site

Summary

The purpose of this retrospective and prospective project is to understand the molecular and genetic basis of liver cancer of childhood. Understanding the molecular and genetic bases of liver cancers can offer a better classification based on tumor biology, mechanisms and predisposition.

Eligibility

Age: 0 Years – 99 YearsHealthy volunteers accepted
Inclusion Criteria:

* Prior or current treatment for a childhood liver tumor, malignant or benign, at age \<21 years.
* Biological parents and siblings of eligible children.

Exclusion Criteria:

* No prior or current treatment for a childhood liver tumor.
* Non-biological parents, legal guardians, or non-biological siblings of eligible children.

Conditions9

CancerChildhood Liver CancerEmbryonal Sarcoma of Liver (Disorder)HepatoblastomaHepatocellular CarcinomaLiver CancerLiver DiseaseLiver Malignant TumorsRhabdoid Tumor of Liver

Locations1 site

UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224
Morgan L Paul, BSN412-692-8472Morgan.Paul2@upmc.edu

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