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SPECT/CT for the Characterization of Renal Masses

RECRUITINGSponsored by Jonsson Comprehensive Cancer Center
Actively Recruiting
SponsorJonsson Comprehensive Cancer Center
Started2018-12-07
Est. completion2025-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

This trial studies how well technetium Tc-99m sestamibi single-photon emission computed tomography/computed tomography (SPECT/CT) works on clinical decision making in patients with kidney tumors. Diagnostic procedures, such as technetium Tc-99m sestamibi SPECT/CT may be a less invasive way to check for kidney tumors.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Performance status Eastern Cooperative Oncology Group (ECOG) \< 2.
* Life expectancy (\> 1 year).
* New diagnosis of a renal tumor (within past 3 months).
* Measurable, predominantly (\> 80%) solid renal neoplasm between 1.5-5.0 cm.
* Lesion concerning for kidney cancer bases on a contrast-enhanced CT or magnetic resonance imaging (MRI).
* No definitive evidence of metastatic disease.
* Does not require urgent surgical treatment.
* Candidate for surgical, ablative, and surveillance approach.
* Willingness to obtain more information to aid decision-making.
* Understanding and willingness to provide consent.

Exclusion Criteria:

* Presence of multiple solid renal tumors.
* A prior needle biopsy of the mass resulting in histologic diagnosis.
* A prior diagnosis of kidney cancer.
* Presence of an active, untreated, non-renal malignancy.
* History of bleeding diathesis or recent bleeding episode.
* Prior surgery or radiation therapy to the kidney.
* Unwillingness to fill out questionnaires.

Conditions3

CancerKidney NeoplasmRenal Mass

Locations1 site

UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095
Brian Shuch310-794-7700BShuch@mednet.ucla.edu

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