RT-CGM in Young Adults at Risk of DKA

Summary

Pilot study to evaluate the effect of real time continuous glucose monitoring (RT-CGM) on young-adults with insulin-treated diabetes, who are defined as high risk due to suboptimal HbA1c (blood glucose control) or a history of hospital admissions for high blood glucoses. Hypothesis: RT-CGM provided to young adults with suboptimal blood glucose control, has a beneficial impact on HbA1c and hospital admissions for high blood glucoses. We will use data from this pilot work to inform a larger powered study to address this knowledge gap.

Eligibility

Inclusion Criteria:

* Adolescents and young adults aged 18-25 years
* Insulin-treated diabetes \>12 months (on multiple daily injections or insulin pump therapy)
* HbA1c \> 75 mmol/mol (9%) or 1 or more DKA admissions in the last 12 months or 1 or more admissions with uncontrolled blood glucose levels in the last 12 months.
* Naïve to RT-CGM - except for short periods for use for diagnosis or monitoring purposes.
* Use of prior flash glucose monitoring is permittable

Exclusion Criteria:

* Chronic kidney disease eGFR \<30ml/min
* Pregnant or planning pregnancy
* Breastfeeding
* Have active malignancy or under investigation for malignancy
* Severe visual impairment
* Reduced manual dexterity
* Unable to participate due to other factors, as assessed by the Chief Investigator

Conditions7

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