Therapeutic Abstention and Surveillance of Intra-epithelial Histological Lesions of High Grade Cervical CIN2 (Cervical Intraepithelial Neoplasia Grade 2). SUIVICIN

Summary

This study proposes to describe and evaluate the rate of spontaneous regression of CIN2 at 2 year of follow up in women between 18 and 39 year old. This follow-up is proposed as an alternative to the treatment of reference (conization) with a possible extension to 4 years

Eligibility

Inclusion Criteria:

* CIN2 confirmed by biopsy, age between 18 and 39 years,
* satisfactory colposcopy identifying the junction and the lesion,
* affiliated person or beneficiary of a social security scheme,
* having given their oral agreement and authorization to the processing of their data.

Exclusion Criteria:

* Pregnancy in progress,
* history of conization,
* atypical or atypical glandular cells or cancer incidentally discovered during smear,
* prophylactic vaccination against HPV,
* active systemic infection requiring treatment, history of HIV infection, congenital or acquired immunodepression,
* long-term treatment with corticosteroids or immunosuppressants, placement under safeguard of justice,
* non-compliance with protocol requirements, in particular a supposed lack of compliance with long-term follow-up

Conditions3

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