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Correlation Between TILs and Blood Cell Counts in Triple Negative Breast Cancer Patients

RECRUITINGSponsored by Centre Jean Perrin
Actively Recruiting
SponsorCentre Jean Perrin
Started2019-12-04
Est. completion2027-10
Eligibility
Age18 Years+
SexFEMALE
Healthy vol.Accepted

Summary

The PERCEPTION study aims to assess the correlation between blood cell counts (Leucocytes, Neutrophils, Lymphocytes, Platelets, NLR (Neutrophil-to-Lymphocyte Ratio) and PLR (Platelet-to-Lymphocyte Ratio)) and Tumor Infiltrating Lymphocytes (TILs), at baseline and after surgery, for patients diagnosed with triple negative breast cancer. It also aims to assess these circulating elements and circulating tumor DNA as predictive factor of metastatic recurrence in triple negative breast cancer.

Eligibility

Age: 18 Years+Sex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* Female
* Age \> 18 years
* Diagnosed with primitive, non-metastatic, histologically proved, triple negative breast cancer
* Patient treated with chemotherapy, surgery and radiation therapy
* Patient able to understand the French language
* Patient affiliated to social security
* Obtaining signed written consent

Exclusion Criteria:

* Male
* Unavailable tumoral samples before inclusion
* Unavailable blood test results at baseline, before inclusion

Conditions3

Breast CancerCancerTriple Negative Breast Cancer

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