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MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics

RECRUITINGN/ASponsored by Mayo Clinic
Actively Recruiting
PhaseN/A
SponsorMayo Clinic
Started2019-10-31
Est. completion2027-01
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* A healthy control will be defined as an otherwise healthy person who does not have a medical condition that affects brain function or have problems with concentration, memory, balance, or coordination.
* Patients who have a suspected diagnosis of altered CSF dynamics including but not limited to normal pressure hydrocephalus will be referred to Dr. Cogswell by their care team to be included in the study. Conditions of altered CSF dynamics include obstructive and non-obstructive hydrocephalus and may be associated with headaches and/or decreased cognitive function.
* Similarly, patients with impaired cognitive function including but not limited to Alzheimer's disease will be referred to Dr. Cogswell by their care team to be included in the study.

Exclusion Criteria:

* Subjects with non-MRI compatible devices
* required sedation
* women who may be pregnant will be excluded.
* The first 10 subjects with normal pressure hydrocephalus will not have previously been shunted.

Conditions3

Alzheimer DiseaseAlzheimer's DiseaseHydrocephalus

Locations1 site

Mayo Clinic
Rochester, Minnesota, 55905
Suson (Sue) WalshWalsh.Suson@mayo.edu

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