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Comparative Imaging Assessment of Valvular Heart Disease

RECRUITINGSponsored by The Cleveland Clinic
Actively Recruiting
SponsorThe Cleveland Clinic
Started2019-08-23
Est. completion2027-12-31
Eligibility
Age18 Years – 90 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT04126018

Summary

The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.

Eligibility

Age: 18 Years – 90 YearsHealthy volunteers accepted
Inclusion Criteria:

* Age 18-90 years of age
* Suspected moderate or severe MR,AR or AS on the basis of prior known clinical history or clinical exam.
* Suspected CRT "non-responder" with an implanted MRI compatible CRT device and reduced ejection fraction

Exclusion Criteria:

* Acute traumatic cardiac injury
* Aortic dissection or aortic root rupture
* Congenital heart diseases such as patent ductus arteriosus, coarctation of aorta, ASD and VSD
* Presence of A-V fistula or intracardiac shunts
* Any contraindications to CMR
* Moderate or severe dysfunction in multiple valves
* Patients with significant claustrophobia

Conditions4

Aortic RegurgitationAortic StenosisHeart DiseaseValve Heart Disease

Locations1 site

Cleveland Clinic
Cleveland, Ohio, 44195
Deborah Kwon, M. D.216-444-8526kwond@ccf.org

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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