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Ruling Out Coronary Artery Disease and Myocardial Injury by Biomarkers

RECRUITINGSponsored by University Hospital, Akershus
Actively Recruiting
SponsorUniversity Hospital, Akershus
Started2019-10-23
Est. completion2023-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT04144725

Summary

A considerable proportion of patients with clinically suspected coronary artery disease (CAD) do not have angiographic signs of luminal narrowing caused by coronary atherosclerosis. In patients with suspected CAD, we will assess the ability of cardiovascular biomarkers to identify patients with (a) angiographically normal epicardial coronary vessels (b) absence of significant epicardial coronary stenosis, as assessed by coronary computed tomography angiography (CCTA). Patients will be stratified according to the presence or absence of dynamic changes of high sensitivity cardiac troponin T levels above the 99th percentile.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Consenting patient over the age of 18 referred to CCTA for suspected coronary artery disease

Exclusion Criteria:

* Inability to provide informed consent.
* Short life expectancy (\<12 months) due to non-cardiovascular disease

Conditions2

Coronary Artery DiseaseHeart Disease

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