COMPuter-assisted Self-training to Improve EXecutive Function

Summary

This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease. The effect of specialized CBCR is compared to generally cognitively stimulating activities on a computer

Eligibility

Inclusion Criteria:

* A diagnose of stroke, cardiac arrest or Parkinson's disease.
* Aged 18 years or older.
* Impaired working memory measured with CABPad working memory test, cut off for inclusion: 5 symbols or less backwards
* Computer and internet access at home.
* Providing informed consent.

Inclusion criteria specific for stroke

* Inclusion within 6 months post-stroke
* Stroke confirmed by clinical findings and imaging, both AIS and ICH is allowed.
* Initial stroke severity \>/= NIHSS 3.

Inclusion criteria specific for cardiac arrest

• Inclusion within 6 months post ictus.

Inclusion criteria specific for Parkinson's disease

* Clinical diagnosis of PD.
* Anti-parkinsonian medical treatment (dopaminergic or other).

Exclusion Criteria:

* Informed consent not provided
* Other neurological or psychiatric disease which is expected to influence the patient's ability to participate in the trial according to the investigator
* Not able to participate according to investigator

Exclusion criteria specific for stroke

* Patients with massive anosognosia for executive dysfunction or patients with no subjective feeling of executive dysfunction (Patient sustains total denial of executive symptoms over time)
* Patients with severe aphasia, in which it is unclear whether the patient's performance on a neuropsychological test-battery is due to aphasia and not executive dysfunction.

Exclusion criteria specific for cardiac arrest • None

Exclusion criteria specific for PD

• Diagnosis of PD Dementia according to the MDS PD Dementia criteria

Conditions7

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