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Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

RECRUITINGSponsored by H. Lee Moffitt Cancer Center and Research Institute
Actively Recruiting
SponsorH. Lee Moffitt Cancer Center and Research Institute
Started2020-02-18
Est. completion2026-06
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations3 sites

Summary

The Florida Pancreas Collaborative wants to partner with individuals who are known to have, or are suspected to have a pancreatic lesion, tumor, cyst, mass, cancer, or pancreatitis and are undergoing diagnosis and treatment at a participating institution. The goals of this project are to build a large database of information obtained from blood, tissue, medical images, surveys and information from routine care to develop noninvasive diagnostic approaches that could be used as decision-making tools to effectively personalize clinical care.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Individuals who present to the GI clinic, surgery, or endoscopy at Moffitt, Florida Research Institute (FRI), or UM with a clinical suspicion for (or diagnosis of) a pancreatic lesion, cyst, mass, cancer, or pancreatitis based on symptoms, imaging, or blood-work and has not had any treatment involving their pancreas.
* Able to understand and voluntarily sign the informed consent.
* Willing to complete study questionnaire(s) and donate medical images and/or biological specimens (including blood, cystic fluid, and/or tissue) obtained at the time of standard of care procedures (biopsy, surgery, and venipuncture) after signing the informed consent document

Exclusion Criteria:

* No suspicion or diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis.
* Has a diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis and has already undergone treatment involving the pancreas (which may involve surgery, chemo- or immuno-therapy, and/or radiation).
* Unable to provide informed consent.
* Unwilling to complete study questionnaire(s) and/or donate biological specimens or images.

Conditions3

CancerPancreatic CancerPancreatic Cyst

Locations3 sites

Florida Research Institute (FRI)
Lakewood Rch, Florida, 34211
Arun Khazanchi, MD941-727-7772arun.khazanchi@fdhs.com
Sylvester Comprehensive Cancer Center & Jackson Memorial Hospital
Miami, Florida, 33136
Nipun B Merchant, MD, FACS305-243-7160nmerchant@miami.edu
Moffitt Cancer Center
Tampa, Florida, 33612
Toni Basinski, MS813-745-6360Toni.Basinski@moffitt.org

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