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Pathogenic Study of Adult Immune Enteropathies

RECRUITINGSponsored by Institut National de la Santé Et de la Recherche Médicale, France
Actively Recruiting
SponsorInstitut National de la Santé Et de la Recherche Médicale, France
Started2020-02-27
Est. completion2030-02-27
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT04280510

Summary

The study focuses the mechanisms underlying the loss of intestinal homeostasis in celiac disease, refractory celiac disease and other immune diseases such as monogenic enteropathy, inflammatory bowel diseases or drug induced intestinal diseases. Mechanisms of transformation of lymphocytes leading to onset of lymphomatous complications of immune enteropathies will be investigated. Mechanisms of loss of hepatic lymphocytic homeostasis will also be assessed in liver associated diseases.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* 18 years or over
* affiliated to social insurance
* signed informed consent

Exclusion Criteria:

* pregnancy
* under guardianship
* not able to sign informed consent

Conditions4

Autoimmune EnteropathyCeliac DiseaseInflammatory Bowel DiseasesLiver Disease

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